Jack Dawson awakens from a terrifying nightmare to find his world under siege. Millions of people have died while he’s lain in a coma in a Norwegian hospital, and the threat of humanity’s total annihilation looms closer with every passing day.

As Jack and his companions face the enemy on the ground, brilliant geneticist Naomi Perrault is forced to strike a bargain with the devil as she races against time to develop a super-weapon that could win the war.